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The Family Lung Cancer
Study
Results of past research studies have suggested that persons in some
families may be genetically more susceptible to developing lung
cancer when exposed to environmental factors such as cigarette
smoke. Scientists at the University of Cincinnati College of
Medicine are working with other scientists throughout the US to find
these susceptibility genes. This large research study is being
conducted by the
Genetic Epidemiology of Lung Cancer Consortium
and is funded by the National Cancer Institute. The University of
Cincinnati portion of the study is known as the Family Lung Cancer
Study. |
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Who should
participate in this study? |
| We are searching for
families with three or more
close blood relatives (parents, brothers, sisters, or grandparents) who have been diagnosed with lung cancer. These
persons may be living or deceased. If the family is eligible, we then
collect information and blood specimens from many family members. |
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Marshall Anderson, Ph.D.
Principal Investigator |
Susan Pinney, Ph.D. Co-Investigator |
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What is involved in being part
of this study? |
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Members of families who participate in
our study are asked to fill out questionnaires about family history of
cancer and cigarette smoking history, and sometimes asked to answer
additional questions in a phone interview. We also ask many family
members to provide us with a blood sample so that we can perform
genotyping. All expenses are paid for by the research project. An
individual may participate in
one or several parts of the study,
depending on the requirements of the study and the preferences of that
person. |
| All questionnaire and genotype
information is maintained in a highly confidential manner, protected by
a
Certificate of
Confidentiality provided by the National Institutes of
Health. Data are then analyzed in the process of searching for the genes
which cause susceptibility to lung cancer. |
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Who would interview me? |
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Our research associate,
Jennifer Baker would
contact you and make all arrangements for participation in the study. |
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I'd like to participate in
the study, who do I contact? |
Please call or email
Jennifer Baker at (513) 558-3120 email
bakejf@uc.edu
We will then send you a
short questionnaire asking about your family history of lung cancer.
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How will the
Family Lung Cancer Study help people with lung cancer?
Identification of the gene that leads to susceptibility to lung
cancer is of major public health significance. Eventually this
knowledge could be used to identify individuals with especially high
risk for lung cancer. These individuals could then be targeted for
early screening programs including a new test,
spiral CT scan,
smoking cessation programs, and perhaps drugs of the future which
would prevent lung cancer. |
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How will my
family’s participation make a difference? |
In our nationwide study, we have worked with literally
hundreds of families as we search for the genes that increase risk for lung
cancer. The cooperation of participating families is crucial for the success
of the Family Lung Cancer Study. The more complete your family tree, the
more accurate and informative your family will be for the study’s
statistical analysis. However, there will be no immediate, direct benefits
from participation in the Family Lung Cancer Study. We hope that the
information you provide will be of benefit to you, your relatives, and
future generations by improved prevention and treatment of lung cancer.
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Where can I go for more
information on support groups for myself and my family? |
Many communities offer
information and
support services for those individuals affected by cancer. Contact your local
United Way or community hospital for suggestions. Many national resources
may also offer information and direct you to local resources.
| Funding for this research
has been provided by: |
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National Cancer Institute
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National Institute of
Environmental Health Sciences (through the Center for Environmental
Genetics)
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Ruth Lyons Fund for Cancer
Research Challenge Grants
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