Alexey, Porollo Alexey Porollo
316 Kettering
Pub Med Articles  

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eLab of Aleksey Porollo


Children's Hospital Medical Center, Cincinnati, OH, USA; 2005 PostDoc in Bioinformatics
Tver State University, Tver, Russia; 1999 PhD in Chemistry
Mari State University, Yoshkar-Ola, Russia; 1995 MSc in Chemistry


2009: Next Generation Biomedical Investigator award, CEG, University of Cincinnati (USA)
2007: University of Cincinnati Research Council award (USA)
2002: German Academic Exchange Service (DAAD) one year scholarship (Germany)
1997: Mari El Republic Presidential post-graduate fellowship (Russia)

Professional Experience

2013-present: Assistant Professor, Center for Autoimmune Genomics and Etiology, Children’s Hosp Med Ctr, Cincinnati, OH, USA
2006-2013: Research Assistant Professor, University of Cincinnati, Cincinnati, OH, USA
2005-2006: Research Associate, Children's Hospital Research Foundation, Cincinnati, OH, USA
2002-2005: Postdoctoral Research Fellow, Children's Hospital Res. Found., Cincinnati, OH, USA
2000-2002: Researcher, Mari State University, Yoshkar-Ola, Russia
1999-2002: Senior Lecturer, Mari State University, Yoshkar-Ola, Russia
1994-1999: Junior Researcher, Mari State University, Yoshkar-Ola, Russia

Selected Publications

Porollo A, Sesterhenn TM, Collins MS, Welge JA, Cushion MT (2014) Comparative Genomics of Pneumocystis Species Suggests the Absence of Genes for myo-Inositol Synthesis and Reliance on Inositol Transport and Metabolism. MBio 5(6):e01834-14.

Fechter K, Porollo A (2014) MutaCYP: Classification of missense mutations in human cytochromes P450. BMC Med Genomics 7(1):47.

Subramanian Vignesh K, Landero Figueroa JA, Porollo A, Caruso JA, Deepe GS Jr (2013) Granulocyte macrophage-colony stimulating factor induced Zn sequestration enhances macrophage superoxide and limits intracellular pathogen survival. Immunity. 39(4):697-710.

Syed K*, Porollo A*, Miller D, Yadav JS (2013) Rational engineering of the fungal P450 monooxygenase CYP5136A3 to improve its oxidizing activity toward polycyclic aromatic hydrocarbons. Protein Eng Des Sel. 26(9):553-557.

Syed K, Porollo A, Lam YW, Grimmett PE, Yadav JS. (2013) CYP63A2, a Catalytically Versatile Fungal P450 Monooxygenase Capable of Oxidizing Higher-Molecular-Weight Polycyclic Aromatic Hydrocarbons, Alkylphenols, and Alkanes. Appl Environ Microbiol 79, 2692-2702.

Ma L, Tao Y, Duran A, Llado V, Galvez A, Barger JF, Castilla EA, Chen J, Yajima T, Porollo A, Medvedovic M, Brill LM, Plas DR, Riedl SJ, Leitges M, Diaz-Meco MT, Richardson AD, Moscat J. (2013) Control of Nutrient Stress-Induced Metabolic Reprogramming by PKCζ in Tumorigenesis. Cell 152, 599-611.

A. Porollo, J. Meller, Y. Joshi, V. Jaiswal, A.G. Smulian, M.T. Cushion (2012) Analysis of Current Antifungal Agents and Their Targets within the Pneumocystis carinii Genome. Curr Drug Targets 13, 1575-1585.

A. Duran, R. Amanchy, J.F. Linares, J. Joshi, S. Abu-Baker, A. Porollo, M. Hansen, J. Moscat, M.T. Diaz-Meco (2011) p62 is a key regulator of nutrient sensing in the mTORC1 pathway. Mol Cell 44, 134-146.

A. Porollo, J. Meller (2007) Prediction-based Fingerprints of Protein-Protein Interactions. Proteins 66, 630-645.

A. Porollo, J. Meller (2007) Versatile Annotation and Publication Quality Visualization of Protein Complexes Using POLYVIEW-3D. BMC Bioinformatics 8, 316 (1-8).

R. Adamczak, A. Porollo, J. Meller (2004) Accurate Prediction of Solvent Accessibility Using Neural Networks Based Regression. Proteins 56, 753-767.

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