Center for Environmental Genetics External Advisory Board              

 

The CEG External Advisory Board (EAB) is comprised of distinguished non-UC scientists who provide a strong
advisory role. They are experts in population studies, human genetics, environmental public health, clinical/translational research and community outreach activities. They all have substantial experience in the administration of large multidisciplinary programs. The EAB meets annually to give an independent review of all components scientific and programmatic progress of the CEG. Review is accomplished through presentations by the Program/Core leaders, and/or the PPP Symposia.

Present EAB committee members are:
Christopher Amos, PhD is Professor and the deputy ad-interim chair of the Department of Epidemiology and leads the Computational and Genetic Epidemiology Section at MD Anderson Cancer Center. He directs the Human Pedigree Analysis Resource, a core facility of the Cancer Center Support Grant, which supports research for individuals with increased familial risk for developing cancer. His research has ranged from investigating familial factors for prostate, head and neck, lung and colon cancers to study of Peutz-Jeghers syndrome, a rare syndrome predisposing to polyps and multiple cancers. Dr. Amos has directed the statistical genetics core for the North American Rheumatoid Arthritis Consortium and the Genetic Epidemiology of Lung Cancer Consortium. He also directs the informatics core of a P01 entitled mutational model for childhood cancer and of a grant from Genome Ontario. Dr. Amos serves as the Secretary/Treasurer for the International Genetic Epidemiology Society and has served as its President. His major research interest lies in the interaction between human genes and the environment. An established leader in the field of environmental genetics and molecular epidemiology, authored over 450 papers, his advice to CEG is invaluable.


David Christiani, MD, MS, MPH, is the Elkan Blout Professor of Environmental Genetics in the Department of Environmental Health at the Harvard School of Public Health and Director of the Environmental Genomics Core at Harvard Environmental Health Sciences Center. Dr. Christiani's major research focus is Molecular Epidemiology of cancer. He has led studies of genetic susceptibility to lung cancer as well as esophageal cancer. His recent work has expanded to biologic markers of polycyclic aromatic hydrocarbon and arsenic exposure in population studies. He has international collaboration on the molecular epidemiology of arsenic-induced bladder and skin cancer, and petrochemical exposures and brain neoplasms and leukemia in children. He conducts large collaborative health research outcome research on three continents: Asia, Africa, and North America, providing expertise and a wide network of and contacts to CEG members as we undertake new studies of the reproductive effects of exposure to chemicals (e.g Chenís project in China).


John DiGiovanni, PhD is the Coulter R. Sublett Chair College of Pharmacy, Div of Pharmacology and Toxicology University of Texas, Austin. He was the former director of the NIEHS Center for Research on Environmental Disease (CRED) at MD Anderson. Research in Dr. DiGiovanniís laboratory focuses on understanding how cancer develops and on the identification of novel targets, mechanisms and strategies for cancer prevention. He is a nationally and internationally well known cancer biologist who has great reputation on gene by environment interaction. His many years of experience in managing the CRED will provide exceptional advice to our Center.


Robin Fuchs-Young, PhD is nationally recognized for her success in designing and managing outstanding community outreach and engagement programs including professional development for science teachers, environmental enhancement of K-12 education, and improvement of scientific literacy and disease prevention in at-risk and underserved communities. She holds or has held titles such as the Associate Director of the Dorothy Height Center for Health Equity and Evaluation Research, Director of the Community Outreach and Education Core (COEC) of the NIEHS Center for Research on Environmental Disease (CRED), and Director of the HHMI Precollege Education Project CENTIPEDe (Community Education Networks to Integrate Prevention of Environmental Disease).


Camille Jones, MD, MPH, CPH is the Assistant Health Commissioner for the City of Cincinnati, and is an Assistant Professor in Public Health Sciences at the University of Cincinnati. Dr. Jones is a public health professional who is interested in prevention of disease, especially lead poisoning. She studies environmental regulations, community health statistics and health promotion in the city of Cincinnati. She bridges the gap between the public health concerns of a major city and the scientific discoveries of the CEG, as her expertise includes both clinical and research efforts in academic and public health settings. She is especially interested in the challenges faced by minority and economically disadvantaged populations, and the social determinants of health. Dr. Jones serves on the Stakeholder Advisory Board for the Center for Environmental Genetics (CEG) Community Outreach and Engagement Core (COEC) and the External Advisory Board of the CEG.


D. Gail McCarver, MD is a Professor of Pharmacology and Toxicology in the Department of Pediatrics at the Medical College of Wisconsin, Co-Director of the Birth Defects Research Center, and Co-Section Chief of Clinical, Pharmacological, Pharmacogenetics & Teratology, Medical College of Wisconsin. She has a longstanding research interest in gene-environment interactions and pregnancy outcomes. Research in Dr. McCarverís lab is on genetically-determined and environmentally-induced differences in xenobiotic metabolism as risk factors for birth defects. She evaluates the ontogeny and genetic contributions to in vivo bisphenol A disposition in NICU infants. Her clinical training and expertise in neonatology, with its close interface with obstetrics, makes her an outstanding EAB to advise CEG on issues related to clinical translation.


Trevor Penning, PhD is Professor of Pharmacology, University of Pennsylvania School of Medicine; he is the Director of the Center of Excellence in Environmental Toxicology (CEET). Dr. Penningís research interests nclude the aldo-keto reductase (AKR) superfamily enzymes and the role they play in cancer. He is also famous on his work in the metabolic activation of polycyclic aromatic hydrocarbon as chemical carcinogens. He applies his research to gene-environmental interaction in many areas including prostate cancer and other reproductive diseases. His experience as the Director of the CEET qualifies him as an excellent External Advisory Board member for the CEG.


Kenneth Ramos, PhD, MD, is a Distinguished University Scholar, Professor of Biochemistry and Molecular Biology and former Director of the Center for Environmental Genomics and Integrative Biology at the University of Louisville. Dr. Ramos is a leading expert in the study of molecular mechanisms of environmental injury and genetic and epigenetic determinants of environmental disease. A major thrust in his laboratory is the study of mammalian retroelements and endogenous retroviral-like sequences. He has longstanding interests in genetic and epigenetic control of mammalian gene expression, environmental genomics, and computational biology, and is a leading expert in the study of molecular mechanisms of environmental disease and gene-gene and gene-environment interactions. His former directorship in an EHS Core Center makes him an outstanding candidate to serve as an EAB member of the CEG.

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